FBI Investigates Prescription Drug Use in Death of Colts Owner Jim Irsay
INDIANAPOLIS, Ind. — Federal authorities have launched an investigation into the circumstances surrounding the death of Jim Irsay, the longtime owner of the Indianapolis Colts, focusing on his use of prescription medications and ketamine treatment administered by a California-based addiction doctor. According to reports, the FBI issued a federal grand jury subpoena earlier this month to obtain records related to Irsay’s medical care and his relationship with Dr. Harry Haroutunian, who treated the Colts owner in the months preceding his death.
The probe reflects growing concerns about the role of prescription drug use and alternative treatments such as ketamine infusions in high-profile deaths. Irsay, who passed away last month, had reportedly been receiving care for addiction issues, and investigators are examining whether any illegal drug use or improper prescribing practices contributed to his demise.
The FBI’s subpoena seeks comprehensive documentation, including medical records and communications between Irsay and Dr. Haroutunian, as part of a broader effort to understand the circumstances that led to the Colts owner’s passing. The investigation underscores the federal government’s increasing scrutiny of prescription drug practices, particularly in cases involving prominent individuals.
Jim Irsay was widely recognized not only for his leadership of the Colts but also for his impact on the NFL and the Indianapolis community. His death has prompted an outpouring of tributes from players, coaches, and fans alike. Yet, the ongoing investigation serves as a reminder of the complex challenges surrounding addiction treatment and the potential risks associated with certain therapies.
Experts note that ketamine, originally developed as an anesthetic, has gained attention in recent years for its off-label use in treating depression and addiction. However, the drug’s administration outside of controlled clinical trials has raised questions about safety and oversight. Federal agencies, including the FBI and the Drug Enforcement Administration, have increased efforts to monitor such treatments amid concerns about misuse.
The investigation into Irsay’s death comes amid heightened awareness of prescription drug abuse nationwide. According to data from the Centers for Disease Control and Prevention, drug overdoses remain a leading cause of injury-related death in the United States, with prescription opioids and other controlled substances playing a significant role.
While the investigation is ongoing, authorities have not released additional details about the findings or whether any charges will be filed. The Colts organization has expressed its condolences and requested privacy for Irsay’s family during this difficult time.
As the federal inquiry proceeds, it highlights the critical importance of responsible prescribing practices and the need for comprehensive oversight in addiction treatment. The case also brings renewed focus to the challenges faced by individuals battling substance use disorders, even those in the public eye.
For more information on prescription drug safety and addiction treatment, the Substance Abuse and Mental Health Services Administration provides resources and guidance.

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