CDC Investigates Gastrointestinal Illness Outbreak on Luxury Cruise Ship

4 February 2026 Lifestyle

MIAMI, Fla. — The U.S. Centers for Disease Control and Prevention (CDC) has launched an investigation into a gastrointestinal illness outbreak aboard the luxury cruise ship Seven Seas Mariner, which was sailing from Miami to Honolulu. The outbreak, which affected 27 individuals including 21 passengers and six crew members, occurred during the month-long voyage that departed on January 11 and concluded on February 1, according to CDC data.

The Seven Seas Mariner, operated by Regent Seven Seas Cruises, was carrying 631 passengers at the time of the outbreak. The itinerary included scheduled port calls in Costa Rica, Guatemala, Mexico, and other destinations. The cruise line promptly notified the CDC of the illnesses during the voyage, triggering the agency’s response.

While the CDC has confirmed the outbreak involved an unknown gastrointestinal illness, the specific cause remains undetermined as investigations continue. Gastrointestinal outbreaks on cruise ships are often associated with norovirus, a highly contagious virus that spreads rapidly in close quarters, but no definitive link has been established in this case. The CDC’s Vessel Sanitation Program routinely monitors and investigates such incidents to protect public health and prevent further transmission.

According to the CDC Vessel Sanitation Program, cruise ships are required to report outbreaks of gastrointestinal illness affecting more than 2% of passengers or crew. The Seven Seas Mariner’s report of 27 cases falls within this threshold, prompting a formal investigation. The CDC works closely with cruise lines to implement control measures, including enhanced sanitation and isolation protocols, to mitigate the spread of illness.

Regent Seven Seas Cruises has not publicly disclosed additional details about the outbreak or the measures taken onboard. However, the company’s cooperation with federal health authorities reflects ongoing efforts within the cruise industry to address health risks associated with large passenger gatherings.

Experts emphasize that gastrointestinal illnesses on cruise ships can be challenging to control due to the confined environment and shared facilities. Passengers and crew are advised to practice rigorous hand hygiene and report symptoms promptly to medical staff. The CDC provides guidance for travelers on its Cruise Ship Travel Health webpage.

This incident marks one of the early gastrointestinal outbreaks reported on cruise vessels in 2026. The CDC’s timely response aims to identify the pathogen responsible and recommend measures to prevent similar outbreaks in the future. As investigations proceed, the agency continues to monitor cruise ship health data and collaborates with the maritime industry to safeguard public health.

For ongoing updates and travel advisories related to cruise ship illnesses, travelers and stakeholders can refer to the CDC’s official resources and the CDC Newsroom.

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Danielle Brooks oversees lifestyle, health and opinion coverage. Her work helps readers think through how policy and culture show up in daily routines, relationships and work-life balance.
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