Serena Williams Shares Transformative Journey with Weight Loss Medication Five Months In
LOS ANGELES, Calif. — Serena Williams, the iconic tennis champion, recently offered a candid update on her health journey, revealing the progress she has made five months after publicly disclosing her use of GLP-1 weight loss medication. In a recent Instagram post, Williams shared a mirror selfie that showcased her slimmer physique, sparking widespread conversation about the role of medication in weight management and overall wellness.
Williams first revealed in August 2025 that she had started taking GLP-1 medication after facing challenges losing weight through diet and exercise following the births of her daughters, Olympia and Adira. Speaking with TODAY at the time, she disclosed that she had been on the treatment for nearly a year and had lost 34 pounds. The GLP-1 class of drugs, approved by the U.S. Food and Drug Administration, is designed to help regulate blood sugar and promote weight loss by mimicking the hormone glucagon-like peptide-1.
In her latest interview with People magazine, Williams described feeling “really good and healthy,” emphasizing the physical and mental lightness she has experienced. “I just can do more,” she said. “I’m more active. My joints don’t hurt as much. I just feel like something as simple as just getting down is a lot easier for me. And I do it a lot faster. I feel like I have a lot of energy, and it’s great.”
Williams also highlighted the broader health benefits beyond weight loss, noting improvements in her blood sugar and cholesterol levels. “It’s more about … not even the weight loss,” she explained, “but it’s about longevity.” She expressed her intention to continue the medication long-term, stating, “I think, for me, GLP-1s are a lifetime thing. There’s a time when you can take it differently, but I feel like it’s just a part of my story and a part of my health journey.”
Her openness comes amid growing public interest in GLP-1 medications, which have been increasingly prescribed for weight management and type 2 diabetes. According to the Centers for Disease Control and Prevention, these medications can play a critical role in improving metabolic health and reducing the risk of chronic conditions.
The tennis star’s update also included a side-by-side comparison of photos: one from March 2025 at the Vanity Fair Oscar Party before she began consistent use of the medication, and a recent snapshot that clearly illustrates the changes she has undergone. Fans and health advocates alike have praised Williams for her transparency, noting how her experience may inspire others to explore medically supervised options for weight and health management.
As public figures like Williams share their health journeys, conversations about the benefits and challenges of weight loss medications continue to evolve. The FDA and CDC provide extensive resources on the safe use of GLP-1 drugs, emphasizing the importance of medical guidance throughout treatment.
For those interested in learning more about GLP-1 medications and their impact on health, official information is available through the FDA and CDC websites.
Serena Williams’s story underscores the intersection of personal health, medical innovation, and the ongoing dialogue about sustainable wellness strategies in the modern era.

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